The effect of plant activators (Salicylic Acid, Acibenzolar S-Methyl, Messenger, ISR 2000, Crop Set, and Fosetyl-Al) applied to root and leaf was investigated in petri and the greenhouse pot experiments against the black root rot disease caused by Rhizoctonia solani on strawberry. As a result of in vitro studies, Salicylic Acid and Fosetyl-Al up to 700 mu g/ml concentration reduced the mycelial development of Rhizoctonia solani, but other plant activators have had no effect on mycelial development of the pathogen. The disease was suppressed between a 47% and 65% ratio by the root dipping application of plant activators Salicylic Acid, Acibenzolar S-Methyl, and Fosetyl-Al. Otherwise, the disease was reduced by a 59% and 65% ratio by foliar applications of Messenger, and Fosetyl-Al. The best plant acitivator is Fosetyl-Al for foliar and root dipping applications. Finally, it has been proved the efficiency of the use of plant activators at the integrated management of black root rot disease caused by Rhizoctonia solani on strawberry.