Effect of Ketamine, Thiopental and Ketamine-Thiopental Combination during Electroconvulsive Therapy for Depression

Kuscu O. O., KARACAER F., BİRİCİK E., GÜLEÇ E., Tamam L., GÜNEŞ KOCAOĞLU Y.

TURKISH JOURNAL OF ANAESTHESIOLOGY AND REANIMATION, vol.43, no.5, pp.313-317, 2015 (ESCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 43 Issue: 5
  • Publication Date: 2015
  • Doi Number: 10.5152/tjar.2015.92668
  • Journal Name: TURKISH JOURNAL OF ANAESTHESIOLOGY AND REANIMATION
  • Journal Indexes: Emerging Sources Citation Index (ESCI), Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.313-317
  • Keywords: Depression, anxiety, thiopental, ketamine, electroconvulsive therapy, TREATMENT-RESISTANT DEPRESSION, MAJOR DEPRESSION, ANTIDEPRESSANT, PROPOFOL, MECHANISMS, ANESTHESIA, EFFICACY
  • Çukurova University Affiliated: Yes

Abstract

Objective: We aimed to evaluate the effect of anaesthesia with thiopental (4 mg kg(-1)), ketamine (1 mg kg(-1)) and ketamine-thiopental (1 mg kg(-1) and 4 mg kg(-1), respectively) combination during electroconvulsive therapy (ECT) on the Hamilton Depression Rating Scale (HDRS) and Hamilton Anxiety Rating Scale (HAM-A) and haemodynamic variables in patients with resistant major depression.