GLASS: Global Lorlatinib for ALK(+) and ROS1(+) retrospective Study: real world data of 123 NSCLC patients


Peled N., Gillis R., KILIÇKAP S., Froesch P., Orlov S., Filippova E., ...Daha Fazla

LUNG CANCER, cilt.148, ss.48-54, 2020 (SCI İndekslerine Giren Dergi) identifier identifier identifier

Özet

Lorlatinib is a third-generation tyrosine-kinases inhibitor (TKI) targeting ALK/ROS1 fusions. The FDA has approved lorlatinib for TKI-pretreated ALK(+) NSCLC, while its approval for ROS1( + ) is still pending. Here we present the largest real-world data of NSCLC patients harboring ALK/ROS1 rearrangements treated with lorlatinib.