Connexin 26 and 30 mutations in paediatric patients with congenital, non-syndromic hearing loss treated with cochlear implantation in Mediterranean Turkey


TARKAN Ö. , SARI P., DEMİRHAN O. , KIROĞLU M. M. , TUNCER Ü. , SÜRMELİOĞLU Ö. , ...Daha Fazla

JOURNAL OF LARYNGOLOGY AND OTOLOGY, cilt.127, ss.33-37, 2013 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 127 Konu: 1
  • Basım Tarihi: 2013
  • Doi Numarası: 10.1017/s0022215112002587
  • Dergi Adı: JOURNAL OF LARYNGOLOGY AND OTOLOGY
  • Sayfa Sayıları: ss.33-37

Özet

Objective: Mutations in the genes for connexin 26 (GJB2) and connexin 30 (GJB6) play an important role in autosomal recessive, non-syndromic hearing loss. This study aimed to detect the 35delG and 167delT mutations of the GJB2 gene and the del(GJB6-D13S1830) mutation of the GJB6 gene in paediatric patients diagnosed with congenital, non-syndromic hearing loss and treated with cochlear implantation in Mediterranean Turkey.