Effect of Skin Antiseptics Used in Peripheral Intravenous Catheter Application on Phlebitis Development: A Double- Blind Randomized Controlled Trial


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KESKİN A., ESKİMEZ Z.

Clinical and Experimental Health Sciences, cilt.14, sa.2, ss.406-413, 2024 (ESCI) identifier

Özet

Objective: This study aimed to examine the effect of antiseptics used in peripheral intravenous catheter (PIVC) application on phlebitis development. Methods: This is a double-blind randomized controlled trial that is suitable for the Consolidated Standards of Reporting Trials (CONSORT) statement. The study was carried out at a University Hospital in Turkey. The study participants were 60 patients (experiments 30 and control 30). 2% chlorhexidine was used as a skin antiseptic in the intervention group and 70% alcohol was used in the control group. In both groups, the catheter insertion site was observed every 8 hours for 72 hour. Data were obtained using the “Personal Information Form” and “Phlebit Scale”. Independent samples t-test (t-table value), Mann–Whitney U test (Z-table value) and Fisher’s exact test, continuity correction, or Pearson’s χ2 cross tables were used for data analysis. Results: No statistically significant difference was found between 2% chlorhexidine and 70% alcohol in preventing the development of phlebitis after PIVC application (p > 0.05). No statistically significant relationship was found between the intervention and control groups in terms of sex, BMI, substance abuse, alcohol use, smoking, chronic disease, or PIVC application area (p>0.05). The highest degree of phlebitis that developed in the intervention and control groups was 1st degree. There was also no statistically significant difference between the groups in terms of degree of phlebitis and phlebitis development time (p > 0.05). Conclusions: In line with the findings obtained from this study, it is thought that both skin antiseptics used when inserting a peripheral intravenous catheter are effective in preventing the development of phlebitis and will guide healthcare personnel in the selection of antiseptics.