In this study, the growth performance and mineral composition of grafted and ungrafted melon plants were studied under salinity stress. In this study, the plant biomass such as total fresh and dry weight, roots and shoots length; and Ca2+, K+, Na+ and Cl- content in leaves, shoots and roots were investigated. Salt stress resulted in the decrease of total fresh and dry weight by 41.75% and 53.62% for ungrafted but this ratio was 17.17% and 19.25% for Maximus F-1/Galia, respectively. The amounts of Na+ and Cl- in leaves of ungrafted plants were very high levels than grafted plants. The effect of salinity was less pronounced in grafted melon plants compared with ungrafted melon plants.