Retina-Vitreus, vol.32, no.2, pp.138-144, 2023 (Scopus)
Purpose: To analyze the microvascular parameters using optical coherence tomography angiography (OCTA) in noninfectious posterior uveitis (PU) patients. Material and Methods: In this cross-sectional study, OCTA images of patients with noninfectious PU were evaluated. The vessel densities (VD) in the superficial and deep capillary plexuses (SCP & DCP), foveal avascular zone (FAZ) area were measured and compared to healthy controls. Results: The study cohort comprised 64 patients with age and gender-matched groups. The VD in the SCP was 43.9±3.9% in the whole image; 18.4±4.8% in the fovea, 43.9±4.6% in the parafoveal area, and 43.4±9.7% in the perifoveal zone, in the eyes with PU. These were respectively 48.8±2.9%, 22.9±6.9%, 50.9±3.0%, and 49.2±3.1% in the control group (p=0.0001, 0.043, 0.0001, 0.01, respectively). The changes in the DCP in eyes with PU were not significant. In the PU group, the FAZ was significantly enlarged compared to controls (0.37±0.1 microns vs. 0.24±0.2 microns, p=0.046). Conclusion: OCTA depicted significant changes, including decreased VD in the SCP and enlarged FAZ in noninfectious PU.