The effects of hypothyroidism on strength-duration properties of peripheral nerve


Yerdelen D., Ertorer E., Koc F.

JOURNAL OF THE NEUROLOGICAL SCIENCES, vol.294, pp.89-91, 2010 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 294
  • Publication Date: 2010
  • Doi Number: 10.1016/j.jns.2010.03.026
  • Journal Name: JOURNAL OF THE NEUROLOGICAL SCIENCES
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.89-91
  • Keywords: Hypothyroidism, Peripheral nerve, Strength-duration time constant, Rheobase, NEUROMUSCULAR FINDINGS, EXCITABILITY, POLYNEUROPATHY, HORMONE, MUSCLE, AXONS
  • Çukurova University Affiliated: Yes

Abstract

Axonal injury and/or demyelination commonly result in peripheral mononeuropathy, polyneuropathy or entrapment neuropathies in hypothyroidism. In this study, we aimed to measure the strength-duration time constants (SDTC) of motor and sensory fibres in patients with primary hypothyroidism before and after hormone replacement treatment. The motor and sensory SDTC and rheobase of 14 patients with overt hypothyroidism (TSH>10 mg/ml, free T4