Severe Pulmonary Toxicity Associated with Fludarabine and Possible Contribution of Rituximab

Disel U., PAYDAŞ S. , Yavuz S., Karakoc E.

CHEMOTHERAPY, cilt.56, sa.2, ss.89-93, 2010 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 56 Konu: 2
  • Basım Tarihi: 2010
  • Doi Numarası: 10.1159/000305255
  • Sayfa Sayıları: ss.89-93


Fludarabine is a nucleoside analogue used in the treatment of low-grade lymphoproliferative disorders and in conditioning regimens of non-myeloablative allogeneic stem cell transplantation. This is a relatively safe drug for clinical use but may cause side effects, some of which may be life-threatening. Here a case of severe pulmonary toxicity associated with fludarabine and a possible contribution of rituximab is presented and the literature reviewed. Copyright (C) 2010 S. Karger AG, Basel