Effect of neutralization of rat interleukin 6 bioactivity on inducible nitric oxide synthase up-regulation and cerebral ischemic damage


TUNA M. , YILMAZ D. M. , ERMAN T. , Arslan A., ÖZGÜR H. , POLAT S.

NEUROLOGICAL RESEARCH, cilt.31, ss.714-720, 2009 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 31 Konu: 7
  • Basım Tarihi: 2009
  • Doi Numarası: 10.1179/174313209x380892
  • Dergi Adı: NEUROLOGICAL RESEARCH
  • Sayfa Sayıları: ss.714-720

Özet

Objectives: Our aim was to investigate whether neutralization of rat interleukin 6 (IL-6) bioactivity attenuates inducible nitric oxide synthase (iNOS) up-regulation and ameliorates cerebral ischemic damage in a model of focal central nervous system (CNS) ischemia.