Effect of neutralization of rat interleukin 6 bioactivity on inducible nitric oxide synthase up-regulation and cerebral ischemic damage

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TUNA M., YILMAZ D. M., ERMAN T., Arslan A., ÖZGÜR H., POLAT S.

NEUROLOGICAL RESEARCH, vol.31, no.7, pp.714-720, 2009 (SCI-Expanded)

• Publication Type: Article / Article
• Volume: 31 Issue: 7
• Publication Date: 2009
• Doi Number: 10.1179/174313209x380892
• Journal Name: NEUROLOGICAL RESEARCH
• Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
• Page Numbers: pp.714-720
• Çukurova University Affiliated: Yes

Abstract

Objectives: Our aim was to investigate whether neutralization of rat interleukin 6 (IL-6) bioactivity attenuates inducible nitric oxide synthase (iNOS) up-regulation and ameliorates cerebral ischemic damage in a model of focal central nervous system (CNS) ischemia.