Survivin and aven: two distinct antiapoptotic signals in acute leukemias


Paydas S. , Tanriverdi K., Yavuz S., Disel U., Sahin B., Burgut R.

ANNALS OF ONCOLOGY, cilt.14, ss.1045-1050, 2003 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 14 Konu: 7
  • Basım Tarihi: 2003
  • Doi Numarası: 10.1093/annonc/mdg277
  • Dergi Adı: ANNALS OF ONCOLOGY
  • Sayfa Sayıları: ss.1045-1050

Özet

Background: Antiapoptotic signals are important in the development, progression and prognosis of malignant tumors. The aim of this study was to determine the two distinct antiapoptotic signals-survivin and aven-in acute leukemias and compare them with clinical and hematological findings and response to therapy. Real-time quantitative PCR was used and survivin and aven were detected at the messenger (m)RNA level.