Akademik Veri Yönetim Sistemi
Journal of Stored Products Research, cilt.115, 2026 (SCI-Expanded, Scopus)
This study aimed at investigating the biological activities (antibacterial, antifungal, and antioxidant), and the chemical profile of essential oil (EO) of Mentha rotundifolia planted in two Moroccan areas (Marrakech and Taounate). EO was extracted from plant leaves by Hydrodistillation and its chemical composition was determined using gas chromatography coupled with mass spectrometry (GC-MS/MS). The antimicrobial activity of extracted EO was tested against numerous microbial strains including bacteria, yeasts, and molds. While the antioxidant activity was assessed by four methods including β-carotene bleaching assay, free radical scavenging activity (DPPH), Ferric reducing antioxidant power (FRAP), and total antioxidant capacity (TAC). Results showed that rotundifolone (C10H14O2) was the major component found in the EO of the plant collected from both studied areas, with 30.12 and 24.51 % in the EO of Marrakech and Taounate, respectively. Furthermore, 27 compounds were identified in the EO of Marrakech, including chlorcarvacrol (15.75 %) and piperitenone (6,09 %). While in the EO of Taounate, only 15 compounds were found including pulegone (19.11 %), and piperitenone (9.23 %). Significant antioxidant activity using the four tests was observed for EO of Marrakech compared to that of Taounate. Moreover, EO of Marrakech has a bactericidal effect, unlike a fungicidal effect observed with the EO of Taounate. These properties could be associated with the identified bioactive compounds in each study area. Molecular docking showed that the ligands synthesized have significant inhibitory potential against the tested strains and possesses strong antibacterial and antifungal activities, making them versatile candidates for developing broad-spectrum antimicrobial agents, and suggest the promising use of essential oil of M. rotundifolia as a natural preservative against a wide range of bacterial and fungal pathogens