A comprehensive review of AI innovations for tackling antimicrobial resistance


Creative Commons License

Alkalaf T., Eker E., Albarri O., Almatar M.

Infezioni in Medicina, cilt.34, sa.3, ss.271-284, 2026 (Scopus)

  • Yayın Türü: Makale / Derleme
  • Cilt numarası: 34 Sayı: 3
  • Basım Tarihi: 2026
  • Doi Numarası: 10.53854/liim-3403-3
  • Dergi Adı: Infezioni in Medicina
  • Derginin Tarandığı İndeksler: Scopus, EMBASE, Biomedical Reference Collection: Corporate Edition (EBSCO)
  • Sayfa Sayıları: ss.271-284
  • Anahtar Kelimeler: Antimicrobial resistance (AMR), Artificial intelligence (AI), Drug Discovery, Infectious diseases, Pathogens
  • Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
  • Çukurova Üniversitesi Adresli: Evet

Özet

Antimicrobial resistance (AMR) represents a major global public health concern, rendering available antimicrobials ineffective and leading to infections that are difficult to treat. Artificial intelligence (AI) has been increasingly applied across the AMR continuum, including resistance prediction, rapid diagnostics, new antimicrobial discovery, drug repurposing, antimicrobial surveillance, and clinical decision support. In this review, we aim to highlight recent developments in the use of artificial intelligence (AI) to address antimicrobial resistance (AMR). In addition, we review computational methods that help interpret genomic, phenomic, clinical, and epidemiological data to support the devel opment of treatment strategies and novel antimicrobial agents. The key issues addressed include data quality, model interpretability, external validation, regulatory requirements, privacy, and fairness. While AI is not a complete solution to AMR, it can certainly strengthen the global AMR response by complementing key areas of AMR such as antimicrobial stewardship, infection prevention, laboratory diagnostics, and global surveillance.