Comparison of in vitro activities of antifungal drugs and ethanolic extract of propolis against Trichophyton rubrum and T-mentagrophytes by using a microdilution assay

Koc A., Silici S., Ayangil D., Ferahbas A., Cankaya S.

MYCOSES, vol.48, no.3, pp.205-210, 2005 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 48 Issue: 3
  • Publication Date: 2005
  • Doi Number: 10.1111/j.1439-0507.2005.01128.x
  • Journal Name: MYCOSES
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.205-210
  • Çukurova University Affiliated: No

Abstract

The in vitro activities of propolis against 29 strains of dermatophytes were compared with those of terbinafine, itraconazole, ketoconazole, and fluconazole. Minimal inhibitory concentrations (MICs) were determined according to a National Committee for Clinical Laboratory Standards broth microdilution method. Among the systemic antifungals tested, terbinafine was the most potent. Propolis showed important antifungal activity and it merits further investigation as a potentially useful agent for the treatment of dermatophytosis.