A Rare and Successfully Managed Complication of Stem Cell Transplantation in an Adult Patient With Sickle Cell Disease: Bone Marrow Necrosis

Ozdogu H., Boga C., Yeral M., Kozanoglu I., GEREKLİOĞLU Ç., Kocer N. E.

Experimental and Clinical Transplantation, cilt.22, sa.11, ss.889-891, 2024 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 22 Sayı: 11
  • Basım Tarihi: 2024
  • Doi Numarası: 10.6002/ect.2021.0170
  • Dergi Adı: Experimental and Clinical Transplantation
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.889-891
  • Anahtar Kelimeler: Bone marrow failure, Hematopoietic stem cell transplantation, Hemoglobin S disease
  • Çukurova Üniversitesi Adresli: Evet

Özet

Sickle cell disease is the most common genetic disorder in the Eastern Mediterranean region where our transplant center is located. Today, adult patients with sickle cell disease can also be successfully treated with allogeneic hematopoietic stem cell transplantation. Bone marrow necrosis is a rare and serious clinical condition. Herein, we present this complication for the first time in the literature, which developed in the course of allogeneic hematopoietic stem cell transplantation and was successfully managed with additional bone marrow support. The recognition, prevention, and management of this rare and potentially fatal complication, bone marrow necrosis, are vitally important, especially in regions with high prevalence of sickle cell disease.