Silent cerebral infarct in patients with mitral valve prolapse

Karakurum B., Topcu S., Yildirim T., Karatas M., Turan I., Tan M., ...More

INTERNATIONAL JOURNAL OF NEUROSCIENCE, vol.115, no.11, pp.1527-1537, 2005 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 115 Issue: 11
  • Publication Date: 2005
  • Doi Number: 10.1080/00207450590957836
  • Page Numbers: pp.1527-1537


It is still not clear whether mitral valve prolapse (MVP) is a risk factor for ischemic stroke. The aim of this study was to evaluate whether uncomplicated MVP is a risk factor for silent cerebral ischemic events. Fifty-two patients with uncomplicated MVP and 46 control subjects without MVP were included in the study. All subjects were evaluated for silent cerebral infarct (SCI) with a magnetic resonance imaging. Five (9.6%) of the patients who had MVP but no other risk factors for ischemic cerebral events had SCI. The results suggest that uncomplicated MVP is a risk factor for SCI, and that patients with MVP should receive anti-platelet-aggregating drugs.