Relation between age and gender differences in plasma triglyceride concentrations and coronary artery disease in Southern Turkey


Acarturk E., Cayli M., Akpinar O., Attila G., Demir M.

CLINICA CHIMICA ACTA, cilt.339, ss.123-128, 2004 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 339
  • Basım Tarihi: 2004
  • Doi Numarası: 10.1016/j.cccn.2003.10.001
  • Dergi Adı: CLINICA CHIMICA ACTA
  • Sayfa Sayıları: ss.123-128

Özet

Background: Coronary artery disease (CAD) is still a leading cause of morbidity and mortality in both genders in Turkey as well as other countries. The role of plasma triglycerides (TG) as a CAD risk factor has been controversial. We investigated the relation between age and gender differences in plasma TG and CAD in patients with angiographically proven CAD. Methods: The study population consisted of 937 patients (605 males and 332 females, aged between 32 and 82 years). The patients were divided into three age groups as <45, 45-59 and greater than or equal to60 years. Risk factors were considered as hypertension, hyperlipidemia, diabetes mellitus, cigarette smoking and family history. Hypertriglyceridemia was defined as TG concentration >150 mg/dl (>1.69 mmol/l). Results: Of the total, 608 had CAD. TG was an independent risk factor for CAD only in women (p < 0.05). There was also a positive correlation between TG concentrations and number of the diseased vessels only in women (p 0.001, r = 0.2). Conclusion: High TG concentrations increase CAD risk more in women than in men in Southern Turkey. Triglycerides should be taken into consideration as an important risk factor especially in women >45 years of age. (C) 2003 Elsevier B.V. All rights reserved.