Treatment of mild-to-moderate hypertension with calcium channel blockers: a multicentre comparison of once-daily nifedipine GITS with once-daily amlodipine


Kes S., Caglar N., Canberk A., Deger N., Demirtas M., Dortlemez H., ...More

CURRENT MEDICAL RESEARCH AND OPINION, vol.19, no.3, pp.226-237, 2003 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 19 Issue: 3
  • Publication Date: 2003
  • Doi Number: 10.1185/030079903125001677
  • Title of Journal : CURRENT MEDICAL RESEARCH AND OPINION
  • Page Numbers: pp.226-237

Abstract

Background: Hypertension is one of the most important causes of cardiovascular disease, and treatment of hypertension leads to a significant reduction in cardiovascular mortality and morbidity. Although calcium channel blockers are regarded as an important part of the therapeutic armamentarium against cardiovascular diseases, and are among the most frequently prescribed anti hypertensive medications, concern has been aroused about these drugs, particularly the short-acting dihydropyridine derivatives. However, the value of nifedipine GITS (Adalat-Crono*), the long-acting dihydropyridine, is in need of being re-established.