Treatment of mild-to-moderate hypertension with calcium channel blockers: a multicentre comparison of once-daily nifedipine GITS with once-daily amlodipine


Kes S., Caglar N., Canberk A., Deger N., Demirtas M., Dortlemez H., et al.

CURRENT MEDICAL RESEARCH AND OPINION, cilt.19, ss.226-237, 2003 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 19 Konu: 3
  • Basım Tarihi: 2003
  • Doi Numarası: 10.1185/030079903125001677
  • Dergi Adı: CURRENT MEDICAL RESEARCH AND OPINION
  • Sayfa Sayısı: ss.226-237

Özet

Background: Hypertension is one of the most important causes of cardiovascular disease, and treatment of hypertension leads to a significant reduction in cardiovascular mortality and morbidity. Although calcium channel blockers are regarded as an important part of the therapeutic armamentarium against cardiovascular diseases, and are among the most frequently prescribed anti hypertensive medications, concern has been aroused about these drugs, particularly the short-acting dihydropyridine derivatives. However, the value of nifedipine GITS (Adalat-Crono*), the long-acting dihydropyridine, is in need of being re-established.