High Catalase and Low Thiol Levels in Adult-ADHD Patients


Alpak G., Selek S., Bulut M., Bulbul F. , Unal A., Virit O., ...Daha Fazla

KLINIK PSIKOFARMAKOLOJI BULTENI-BULLETIN OF CLINICAL PSYCHOPHARMACOLOGY, cilt.24, sa.2, ss.128-134, 2014 (SCI İndekslerine Giren Dergi) identifier identifier

  • Cilt numarası: 24 Konu: 2
  • Basım Tarihi: 2014
  • Doi Numarası: 10.5455/bcp.20140429091127
  • Dergi Adı: KLINIK PSIKOFARMAKOLOJI BULTENI-BULLETIN OF CLINICAL PSYCHOPHARMACOLOGY
  • Sayfa Sayıları: ss.128-134

Özet

Objective: The prevalence of Adult attention-deficit/hyperactivity disorder (A-ADHD) has been estimated as to be around 5%. There are several hypotheses regarding the etiology of ADHD. Although numerous researches have been conducted regarding neurobiology of pediatric ADHD, A-ADHD studies were relatively few. Many studies have indicated that oxidant mediated neuronal damage may play a role in the pathophysiology of various psychiatric disorders. Recently, oxidative stress has been studied in A-ADHD and there is an accumulating evidence to support its' role. In the present study, we aimed to evaluate catalase (CAT) and thiol levels in A-ADHD patients and compare with healthy controls.