Autosomal Dominant Polycystic Disease is Associated with Depressed Levels of Soluble Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand

SARI F. , YALCIN A. D. , Genc G. E. , SARIKAYA M., Bisgin A., CETINKAYA R., et al.

BALKAN MEDICAL JOURNAL, cilt.33, ss.512-516, 2016 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 33 Konu: 5
  • Basım Tarihi: 2016
  • Doi Numarası: 10.5152/balkanmedj.2016.150685
  • Dergi Adı: BALKAN MEDICAL JOURNAL
  • Sayfa Sayısı: ss.512-516

Özet

Background: Autosomal dominant polycystic kidney disease (ADPKD) is characterized by multiple, large renal cysts and impaired kidney function. Although the reason for the development of kidney cysts is unknown, ADPKD is associated with cell cycle arrest and abundant apoptosis of renal tubular epithelial cells.