Autosomal Dominant Polycystic Disease is Associated with Depressed Levels of Soluble Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand

SARI F. , YALCIN A. D. , Genc G. E. , SARIKAYA M., Bisgin A., CETINKAYA R., ...More

BALKAN MEDICAL JOURNAL, vol.33, no.5, pp.512-516, 2016 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 33 Issue: 5
  • Publication Date: 2016
  • Doi Number: 10.5152/balkanmedj.2016.150685
  • Title of Journal : BALKAN MEDICAL JOURNAL
  • Page Numbers: pp.512-516


Background: Autosomal dominant polycystic kidney disease (ADPKD) is characterized by multiple, large renal cysts and impaired kidney function. Although the reason for the development of kidney cysts is unknown, ADPKD is associated with cell cycle arrest and abundant apoptosis of renal tubular epithelial cells.