Autosomal Dominant Polycystic Disease is Associated with Depressed Levels of Soluble Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand

SARI, ATIL; YALCIN, Arzu; Genc, Gizem; SARIKAYA, Metin; Bisgin, Atil; CETINKAYA, Ramazan; GÜMÜŞLÜ, SAADET

doi:10.5152/balkanmedj.2016.150685

Autosomal Dominant Polycystic Disease is Associated with Depressed Levels of Soluble Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand

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SARI F. , YALCIN A. D. , Genc G. E. , SARIKAYA M., Bisgin A., CETINKAYA R., ...More

BALKAN MEDICAL JOURNAL, vol.33, no.5, pp.512-516, 2016 (Journal Indexed in SCI)

Publication Type: Article / Article
Volume: 33 Issue: 5
Publication Date: 2016
Doi Number: 10.5152/balkanmedj.2016.150685
Title of Journal : BALKAN MEDICAL JOURNAL
Page Numbers: pp.512-516

Abstract

Background: Autosomal dominant polycystic kidney disease (ADPKD) is characterized by multiple, large renal cysts and impaired kidney function. Although the reason for the development of kidney cysts is unknown, ADPKD is associated with cell cycle arrest and abundant apoptosis of renal tubular epithelial cells.