Autosomal Dominant Polycystic Disease is Associated with Depressed Levels of Soluble Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand

SARI, ATIL; YALCIN, Arzu; Genc, Gizem; SARIKAYA, Metin; Bisgin, Atil; CETINKAYA, Ramazan; GÜMÜŞLÜ, SAADET

doi:10.5152/balkanmedj.2016.150685

Autosomal Dominant Polycystic Disease is Associated with Depressed Levels of Soluble Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand

Atıf İçin Kopyala

SARI F. , YALCIN A. D. , Genc G. E. , SARIKAYA M., Bisgin A., CETINKAYA R., ...Daha Fazla

BALKAN MEDICAL JOURNAL, cilt.33, ss.512-516, 2016 (SCI İndekslerine Giren Dergi)

Cilt numarası: 33 Konu: 5
Basım Tarihi: 2016
Doi Numarası: 10.5152/balkanmedj.2016.150685
Dergi Adı: BALKAN MEDICAL JOURNAL
Sayfa Sayıları: ss.512-516

Özet

Background: Autosomal dominant polycystic kidney disease (ADPKD) is characterized by multiple, large renal cysts and impaired kidney function. Although the reason for the development of kidney cysts is unknown, ADPKD is associated with cell cycle arrest and abundant apoptosis of renal tubular epithelial cells.