This research was conducted at GAP Agricultural Research Center of Turkish Ministry of Agriculture and Rural Affairs in Sanliurfa-Turkey between 2011 and 2012 in pots under non heated greenhouse condition to determine effects of salinity on eight Cucurbita pepo genotypes collected from different locations of Sanliurfa-Turkey. At the 4-5 true leaves, salt treatments were applied. Non salt plots continued from sowing to harvest as a control plot. Both quality and physiologic/vegetative characteristics were measured such as leaf temperature, leaf area, yield, TSSC, mean fruit weight, mean fruit height, fruit diameter and dry root weight/fresh root weight were tested at two years. Also final drought resistance tests were examined. The research had four salinity categories in order to determine salt effect on genotypes (50 mmol, 100 mmol, 150 mmol and the control at 0 mmol) were applied. Class A pan used for determining amount of water for irrigation. At the end of the experiment all genotypes died at 100 mmol and 150 mmolsalt. Applying 50 mmol salt injured most of genotypes except number 8 (Sanliurfa Mrkz.).