Akademik Veri Yönetim Sistemi
Forensic Science International: Genetics Supplement Series, cilt.3, sa.1, 2011 (Scopus)
We found 38 intermediate alleles of DYS458 locus in a 249 Turkish population samples. We have examined the molecular structure of these allelic variants and association of J1 haplogroup, using by sequence analyses. Analysis results showed that all of the samples with DYS458.2 variant have incomplete repeat caused by an AA insertion or GA deletion in front of the third repeat form from the last and have M267 Single Nucleotide Polymorphism (SNP) specific to haplogroup J1. This finding is supportive to common origin for the DYS458.2 allelic variants. We have also observed that all of the 38 samples have been shared the same alleles at some Y-chromosome Short Tandem Repeat (Y-STR) loci when we have examined 17-YSTRs loci in our population data. These alleles are DYS392*11, DYS393*12, DYS438*10 and DYS458.2 variants. Complete dependency was detected noteworthy between DYS458.2 variants and three loci; DYS392*11, DYS393*12 and DYS438*10 respectively, related with the same origin. However, further studies should be done with more additional samples. © 2011 Elsevier Ireland Ltd.