Detection of Hepatitis B Virus Drug Resistance Mutations By Pyrosequencing Method


Cimentepe M., Yildirm D., KÖMÜR S., Sefleki B., Sagdic D. O., YARKIN F.

MEDITERRANEAN JOURNAL OF INFECTION MICROBES AND ANTIMICROBIALS, cilt.7, 2018 (ESCI) identifier identifier identifier

Özet

Introduction: The development of drug resistance mutations to nucleos(t)ide analogues during long term therapy of chronic hepatitis B virus (HBV) infection is a major concern leading to treatment failure. The aim of this study is to investigate of HBV drug resistance gene mutations in patients with chronic hepatitis B infection by pyrosequencing method.