ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY, vol.17, no.10, pp.1426-1433, 2017 (Journal Indexed in SCI)
Article / Article
Title of Journal :
ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY
Chalcone, cytotoxicity, dimethoxy, difluoro, potency selectivity expression, dental cells, PARP, MOLECULAR TARGET PERSPECTIVES, MANNICH BASE DERIVATIVES, CARBONIC-ANHYDRASE I, CANCER CELLS, INHIBITORS, ACETYLCHOLINESTERASE, APOPTOSIS
Background: Although anticancer chemotherapeutics are available in markets, side effects related to the drugs in clinical use lead to researchers to investigate new drug candidates which are more safe, potent and selective than others. Chalcones are popular with their anticancer activities with the several reported mechanisms including inhibition of angiogenesis, inhibition of tubulin polymerization, and induction of apoptosis etc.