Effect of prophylactic beta-glucan use on the incidence of neutropenic fever and survival rates in pediatric patients with sarcoma

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ÖZKAN A., KÜPELİ S., Cil M., SEZGİN G., BAYRAM İ.

CUKUROVA MEDICAL JOURNAL, cilt.47, sa.2, ss.596-602, 2022 (ESCI) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 47 Sayı: 2
  • Basım Tarihi: 2022
  • Doi Numarası: 10.17826/cumj.1039267
  • Dergi Adı: CUKUROVA MEDICAL JOURNAL
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Academic Search Premier, Directory of Open Access Journals, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.596-602
  • Anahtar Kelimeler: Beta-glucan, neutropenic fever, pediatric sarcomas, survival, CANCER, OSTEOSARCOMA, CHEMOTHERAPY, GUIDELINE, BLOOD
  • Çukurova Üniversitesi Adresli: Evet

Özet

Purpose: Some patients with cancer use herbal therapy as an adjunct while receiving conventional cancer treatments. Beta-glucans have direct cytotoxic effects on cancer cells as well as stimulatory effects on the immune system. In this study, a nutritional supplement containing 1,3-1,6 beta-glucan obtained from baker's yeast (Saccharomyces cerevisiae) was used by patients diagnosed with sarcoma, and this study aimed to retrospectively evaluate the effect of beta-glucan use on the incidence of neutropenic fever (NF) and survival rates.