Risk of developing fibroadenoma with the use of cyclosporine A in renal transplant recipients

BINOKAY F., BALAL M., DEMIR E., Paydas S., SOYUPAK S., SERTDEMIR Y., ...More

RENAL FAILURE, vol.27, no.6, pp.721-725, 2005 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 27 Issue: 6
  • Publication Date: 2005
  • Doi Number: 10.1080/08860220500243197
  • Journal Name: RENAL FAILURE
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.721-725
  • Çukurova University Affiliated: Yes

Abstract

To investigate the effect of cyclosporine A (Cyc A) on the development of fibroadenomas, 30 renal transplant patients and 20 chronic renal failure patients on dialysis were breast examined with ultrasonography and/or mammography. Of the renal transplant patients, 17 were receiving Cyc A-based combination therapy for immunosuppression. All patients were female with the age range of 29.7 +/- 9.2 years in the transplant group and 33.95 +/- 9.91 in the dialysis group. Eight of the 17 patients receiving Cyc A had fibroadenomas, 5 of them having bilateral lesions. None of the other patients, those on dialysis and on non-Cyc A combination therapy had fibroadenomas. A significant difference for fibroadenoma incidence in patients receiving Cyc A combination immunosuppression was found.