Protective effect of L-arginine on gentamicin-induced nephrotoxicity in rats

Bashan B., Bashan P., SEÇİLMİŞ M. A., ŞİNGİRİK E.

INDIAN JOURNAL OF PHARMACOLOGY, cilt.46, sa.6, ss.608-612, 2014 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 46 Sayı: 6
  • Basım Tarihi: 2014
  • Doi Numarası: 10.4103/0253-7613.144915
  • Dergi Adı: INDIAN JOURNAL OF PHARMACOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.608-612
  • Çukurova Üniversitesi Adresli: Evet

Özet

Introduction: L-arginine has a protective effect on gentamicin-induced renal failure and it may decrease the tubular reabsorption of another cationic substance, gentamicin due to its cationic structure. The aim of this study is to compare the possible protective effects of L-arginine and its inactive isomer D-arginine on gentamicin-induced nephrotoxicity in rats.