Prognostic significance of EGFR, MUC1 and PD-L1 expressions in cases with triple negative breast cancer


MİRİLİ C. , PAYDAŞ S. , BAĞIR KILIÇ E. , SEYDAOĞLU G. , OĞUL A. , GÖKÇAY S. , ...More

JOURNAL OF BUON, vol.25, no.1, pp.159-167, 2020 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 25 Issue: 1
  • Publication Date: 2020
  • Title of Journal : JOURNAL OF BUON
  • Page Numbers: pp.159-167
  • Keywords: EGFR, MUC1, PD-L1, triple negative breast cancer, prognosis, TUMOR-INFILTRATING LYMPHOCYTES, CLINICAL-FEATURES, ONCOPROTEIN, ACTIVATION, MUCINS, CARCINOMA, SURVIVAL

Abstract

Purpose: Twenty percent of the breast cancers are triple negative (TNBC). Despite the impressive progression in the biology of this subgroup, data is limited as compared to hormone and/or HER2 positive cases. Thus, the aim of this study was to detect the expression levels and to identify the prognostic values of MUC1, EGFR and PD-L1 in TNBC.