Prognostic significance of EGFR, MUC1 and PD-L1 expressions in cases with triple negative breast cancer

MİRİLİ C., PAYDAŞ S., BAĞIR KILIÇ E., SEYDAOĞLU G., OĞUL A., GÖKÇAY S., ...More

JOURNAL OF BUON, vol.25, no.1, pp.159-167, 2020 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 25 Issue: 1
  • Publication Date: 2020
  • Journal Name: JOURNAL OF BUON
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE, MEDLINE
  • Page Numbers: pp.159-167
  • Keywords: EGFR, MUC1, PD-L1, triple negative breast cancer, prognosis, TUMOR-INFILTRATING LYMPHOCYTES, CLINICAL-FEATURES, ONCOPROTEIN, ACTIVATION, MUCINS, CARCINOMA, SURVIVAL
  • Çukurova University Affiliated: Yes

Abstract

Purpose: Twenty percent of the breast cancers are triple negative (TNBC). Despite the impressive progression in the biology of this subgroup, data is limited as compared to hormone and/or HER2 positive cases. Thus, the aim of this study was to detect the expression levels and to identify the prognostic values of MUC1, EGFR and PD-L1 in TNBC.