Effects of cyclopamine and temozolomide combined treatment on miR-20a expression in glioblastoma cell line (U87)

Creative Commons License

SENCAR L., Yilmaz D. M., Gokturk D., Polat S., COŞKUN G., ŞAKER D., ...More

CUKUROVA MEDICAL JOURNAL, vol.46, no.4, pp.1426-1432, 2021 (ESCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 46 Issue: 4
  • Publication Date: 2021
  • Doi Number: 10.17826/cumj.996520
  • Journal Indexes: Emerging Sources Citation Index (ESCI), Academic Search Premier, Directory of Open Access Journals, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.1426-1432
  • Keywords: Glioblastoma, cyclopamine, temozolomide, MiR-20a, INHIBITION, MICRORNAS, CANCER, TUMORIGENESIS, MULTIFORME, MIGRATION, HEDGEHOG
  • Çukurova University Affiliated: Yes


Purpose: The aim of this study was to investigate miR-20a expression in glioblastoma cell line (U87) after applying cyclopamine and temozolomide (TMZ) treatment separately and in combination and to evaluate the efficiency of miR-20a in glioblastoma treatment.