The Effects of Oxcarbazepine on 4-Aminopyridine-Induced Afterpotentials on Isolated Rat Sural Nerves

GÜVEN M., Kahraman I., Koc F., BOZDEMİR H., Sarica Y., GÜNAY İ.

JOURNAL OF NEUROLOGICAL SCIENCES-TURKISH, vol.27, no.2, pp.139-149, 2010 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 27 Issue: 2
  • Publication Date: 2010
  • Journal Name: JOURNAL OF NEUROLOGICAL SCIENCES-TURKISH
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.139-149
  • Çukurova University Affiliated: Yes

Abstract

Objective: Oxcarbazepine is used for the treatment of neuropathic pain syndromes. In the present study, we have investigated the effect of oxcarbazepine on the amplitude of compound action potentials (CAP), and the depolarizing after-potentials induced by 4-aminopyridine in the rat sural nerves which plays an important role of the neuropathic pain. Material and