Diagnostic Modalities Based on Flow Cytometry for Chronic Granulomatous Disease: A Multicenter Study in a Well-Defined Cohort.


Baris H., Ogulur I., Akcam B., Kiykim A., Karagoz D., Saraymen B., ...Daha Fazla

The journal of allergy and clinical immunology. In practice, cilt.8, 2020 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 8
  • Basım Tarihi: 2020
  • Doi Numarası: 10.1016/j.jaip.2020.07.030
  • Dergi Adı: The journal of allergy and clinical immunology. In practice
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE, MEDLINE
  • Anahtar Kelimeler: Chronic granulomatous disease, NADPH oxidase, flow cytometry, Dihydrorhodamine, gp91, p22, p47, p67, MUTATIONS, DIHYDRORHODAMINE, OXIDASE, ASSAY, FAMILIES, CARRIERS, TURKEY, BURST
  • Çukurova Üniversitesi Adresli: Evet

Özet

BACKGROUND: Chronic granulomatous disease (CGD) is characterized by defective microbial killing due to mutations affecting subunits of the nicotinamide adenine dinucleotide phosphate (NADPH) oxidase complex. Definitive genetic identification of disease subtypes may be delayed or not readily available.