Serum nectin-2 levels are diagnostic and prognostic in patients with colorectal carcinoma

KARABULUT M., GUNALDI M., ALIS H., Afsar C. U., Karabulut S., SERİLMEZ M., ...Daha Fazla

CLINICAL & TRANSLATIONAL ONCOLOGY, cilt.18, sa.2, ss.160-171, 2016 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 18 Sayı: 2
  • Basım Tarihi: 2016
  • Doi Numarası: 10.1007/s12094-015-1348-1
  • Dergi Adı: CLINICAL & TRANSLATIONAL ONCOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.160-171
  • Çukurova Üniversitesi Adresli: Hayır

Özet

Nectins are a family of integral protein and immunoglobulin-like cell adhesion molecules involved in the formation of functioning adherence and tight junctions. Aberrant expression is associated with cancer progression, apoptosis and cell proliferation but little is known how these effects change in cell behavior. The objective of this study was to evaluate the serum levels of nectin-2 with regard to diagnostic, predictive and prognostic value in colorectal cancer (CRC) patients.