Effect of neutralization of rat interleukin 6 bioactivity on inducible nitric oxide synthase up-regulation and cerebral ischemic damage

TUNA, METİN; YILMAZ, DERVİŞ; ERMAN, TAHSİN; Arslan, Ali; ÖZGÜR, HÜLYA; POLAT, SAİT

doi:10.1179/174313209x380892

Effect of neutralization of rat interleukin 6 bioactivity on inducible nitric oxide synthase up-regulation and cerebral ischemic damage

TUNA M., YILMAZ D. M., ERMAN T., Arslan A., ÖZGÜR H., POLAT S.

NEUROLOGICAL RESEARCH, cilt.31, sa.7, ss.714-720, 2009 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 31 Sayı: 7
Basım Tarihi: 2009
Doi Numarası: 10.1179/174313209x380892
Dergi Adı: NEUROLOGICAL RESEARCH
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.714-720
Çukurova Üniversitesi Adresli: Evet

Özet

Objectives: Our aim was to investigate whether neutralization of rat interleukin 6 (IL-6) bioactivity attenuates inducible nitric oxide synthase (iNOS) up-regulation and ameliorates cerebral ischemic damage in a model of focal central nervous system (CNS) ischemia.