NERVUS OPTICUS VE CRANIUM'UN SAĞLIKLIBİREYLERDE ANATOMİK VE RADYOLOJİK OLARAK MORFOMETRİSİNİN DEĞERLENDİRİLMESİ


Thesis Type: Postgraduate

Institution Of The Thesis: Cukurova University, Sağlık Bilimleri Enstitüsü, Temel Tıp Bilimleri, Turkey

Approval Date: 2023

Thesis Language: Turkish

Student: MAHMUT TUNÇ

Supervisor: Pınar Göker

Abstract:

In this study, it was aimed to determine the reference values of the morphometric measurements of the nervus opticus (n) and cranium in healthy individuals according to age and gender and investigation of the relationship of n.opticus morphometry with the cranium. Also, sagittal, axial and coronal Magnetic Resonance Images (MRI) of the brain region of 559 healthy individuals, 280 females and 279 males, aged between 02 and 90 years, who applied to the Radiology Department of Bozyaka Training and Research Hospital between 2018 and 2022 for various reasons, were retrospectively analyzed. Bulbus oculi transverse diameter, nervus opticus sheath thickness, chiasma opticum length and width, and cranium morphometric measurements of all individuals participating in the study were taken using an electronic caliper. Mean ±standard deviation, maximum (max.) and minimum (min.) values were obtained by using the IBM SPSS Statistics 22.0 program for the measurement results of the participants included in the study. Significance level was accepted as p<0.05. Age and gender-related changes in the measurements were determined. There was a significant difference between the genders in all measurements except for the width of the chiasma opticum (p<0.05). However, all measurement values ​​were higher in males than females, except for clival angle. According to the result of Pearson Correlation Analysis, which determining of the relationship presence between nervus opticus sheath thickness and craniometric measurements, a weak level but significant correlation was found between nervus opticus sheath thickness and craniometric measurements (r<0.4; p<0.05). In the Post Hoc test performed to compare the decades with each other, it was observed that the clear changes in our measurements were in the 02-10 age range and the measurement values decreased in the old age. The knowledge of the nervus opticus sheath thickness and craniometric values ​​will be very helpful in terms of early diagnosis of related diseases and guiding surgical interventions in this region. We think that revealing the age and gender related changes in the nervus opticus and cranium morphometry of our population anatomically and radiologically will be an important source in terms of creating reference values ​​for our society.