Research Information System
Thesis Type: Postgraduate
Institution Of The Thesis: Cukurova University, Sağlık Bilimleri Enstitüsü, Temel Tıp Bilimleri, Turkey
Approval Date: 2023
Thesis Language: Turkish
Student: MAHMUT TUNÇ
Supervisor: Pınar Göker
Abstract:
In
this study, it was aimed to determine the reference values of the morphometric
measurements of the nervus opticus (n) and cranium in healthy individuals
according to age and gender and investigation of the relationship of n.opticus
morphometry with the cranium. Also, sagittal, axial and coronal Magnetic
Resonance Images (MRI) of the brain region of 559 healthy individuals, 280
females and 279 males, aged between 02 and 90 years, who applied to the
Radiology Department of Bozyaka Training and Research Hospital between 2018 and
2022 for various reasons, were retrospectively analyzed. Bulbus oculi transverse
diameter, nervus opticus sheath thickness, chiasma opticum length and width,
and cranium morphometric measurements of all individuals participating in the study
were taken using an electronic caliper. Mean ±standard deviation, maximum (max.)
and minimum (min.) values were obtained by using the IBM SPSS Statistics 22.0
program for the measurement results of the participants included in the study.
Significance level was accepted as p<0.05. Age and gender-related changes in
the measurements were determined. There was a significant difference between
the genders in all measurements except for the width of the chiasma opticum (p<0.05).
However, all measurement values were higher in males than females, except for
clival angle. According to the result of Pearson Correlation Analysis, which
determining of the relationship presence between nervus opticus sheath
thickness and craniometric measurements, a weak level but significant
correlation was found between nervus opticus sheath thickness and craniometric
measurements (r<0.4; p<0.05). In the Post Hoc test performed to compare
the decades with each other, it was observed that the clear changes in our
measurements were in the 02-10 age range and the measurement values decreased
in the old age. The knowledge of the nervus opticus sheath thickness and
craniometric values will be very helpful in terms of early diagnosis of
related diseases and guiding surgical interventions in this region. We think
that revealing the age and gender related changes in the nervus opticus and
cranium morphometry of our population anatomically and radiologically will be
an important source in terms of creating reference values for our society.