Research Information System
Thesis Type: Expertise In Medicine
Institution Of The Thesis: Cukurova University, Tıp Fakültesi, Temel Tıp Bilimleri, Turkey
Approval Date: 2024
Thesis Language: Turkish
Student: ESRA BOLAT
Supervisor: Pınar Göker
Abstract:
This study aimed to
determine skull cortical thickness changes in schizophrenia patients, compare
them with the control group, and evaluate them in terms of age and gender. For
this aim, who applied to Kozan State Hospital Radiology Department for various
reasons between 2018-2022 axial Computed Tomography (CT) images of the brain
regions of 30 individuals,12 female and 18 male aged 18-69 years, who diagnosed
with schizophrenia and xial CT images of the brain region of 132 healthy
individuals, 69 male and 63 female aged 18-75 years, were retrospectively
examined. Age,
gender, skull length, skull width, anterior thickness, right anterior cortical
thickness, left anterior cortical thickness, right lateral cortical thickness,
left lateral cortical thickness, right posterior lateral thickness, left
posterior lateral thickness and posterior cortical thickness of the individuals
participating in the study were measured by electronic caliper on axial CT. Mean
±standard deviation, maximum (max.) and minimum (min.) values were obtained by
using the IBM SPSS Statistics 22.0 program for the measurement results of the
participants included in the study. Significance level was accepted as
p<0.05. Measurements were also evaluated according to gender. In our study,
while there was no statistically significant difference between the patient
group and the control group in skull width, skull length, anterior cortical
thickness, right anterior cortical thickness, left anterior cortical thickness,
right lateral cortical thickness and left lateral cortical thickness
measurements (p>0.05), there was a statistically significant difference was
observed between the two groups in the measurements of right posterior lateral
thickness, left posterior lateral thickness and posterior cortical thickness
(p<0.05). In our study, genders were compared, and skull width, anterior
thickness, left anterior thickness, right posterior thickness and left
posterior thickness measurements in the patient group showed a statistically
significant difference from the control group (p<0.05). We think that this study will make a
significant contribution to the literature as it is the first study to measure
the cortical bone thickness of schizophrenia patients. We also think that our
study will be an important resource in establishing reference values for our
population.